Oxycodone (active chemical)
- IUPAC name:
4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one - Molecular formula:
C₁₈H₂₁NO₄ - Chemical class:
- Semi-synthetic opioid
- Derived from the morphinan / phenanthrene scaffold
- Structurally related to thebaine (an opium alkaloid)
Key structural features
- A rigid four-ring (phenanthrene/morphinan) backbone
- An epoxy bridge (4,5-epoxy) in the ring system
- A ketone group at C6 (6-one)
- A methoxy group (-OCH₃) at position 3
- A hydroxyl group (-OH) at position 14
- A tertiary amine (N-methyl) in the structure
Pharmacological chemical class
- μ-opioid receptor agonist
- Interacts primarily with the mu-opioid receptor (MOR), producing analgesic effects by mimicking endogenous opioid peptides




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