Ecstasy commonly refers to MDMA, whose full chemical name is:
3,4-methylenedioxymethamphetamine (MDMA)
Chemical description
MDMA is a synthetic psychoactive compound in the substituted amphetamine class. Its structure is based on an amphetamine backbone with two key features:
- A methylenedioxy group attached to the benzene ring at positions 3 and 4
- A N-methyl group on the amine side chain (making it a methylated amphetamine)
Molecular formula
C₁₁H₁₅NO₂
Structural characteristics
- Contains a phenethylamine core (common to stimulants like amphetamine)
- The methylenedioxy ring (–O–CH₂–O–) forms a rigid dioxole structure fused to the aromatic ring
- Has a chiral center, meaning it exists as two enantiomers (R and S forms), with the S-enantiomer generally being more psychoactive
Chemical class
- Substituted phenethylamine
- Substituted amphetamine
- Entactogen / empathogen (pharmacological class)
Basic physicochemical properties
- Typically exists as a white crystalline solid in pure form
- Often encountered as salt forms (commonly hydrochloride) which are more stable and water-soluble
- Moderately lipophilic, allowing it to cross the blood–brain barrier efficiently
Mechanism at a chemical level (brief)
MDMA acts primarily by interacting with monoamine transporters:
- Promotes release and blocks reuptake of serotonin (5-HT), and to a lesser extent dopamine and norepinephrine
- Causes a large increase in extracellular serotonin, which drives its psychoactive effects




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