MDMA (Ecstasy)
- Chemical name (IUPAC):
3,4-methylenedioxy-N-methylamphetamine - Molecular formula:
C₁₁H₁₅NO₂ - Chemical class:
- Substituted phenethylamine
- Substituted amphetamine
- Functionally classified as an entactogen/empathogen
- Key structural features:
- A benzene ring with a methylenedioxy bridge (–O–CH₂–O–) at positions 3 and 4
- A two-carbon side chain (phenethylamine backbone)
- A methylated amine group (–NHCH₃)
- One chiral center → exists as R/S enantiomers (S-enantiomer is more active)
- Pharmacological chemistry (brief):
MDMA acts primarily by increasing extracellular monoamines, especially serotonin (5-HT), by reversing transporter proteins (SERT, DAT, NET).




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